HSCI
367 Human Disease Mechanism
Spring,
2000
Class
meeting times:
MWF 12:00 to 1:10 PM, TC 28
Instructor:
Dorothy C. Chen-Maynard, Ph.D., R.D.
Office:
HP 130
Office
telephone:
(909) 537-5340
Office
hours Spring quarter:
Mondays: 10:00 to 11:30 AM, Tuesdays 10:00-11:00 AM, and by
appointment
Required
Textbook:
Pathology for the Health-Related Professions, 2nd Ed.,
Ivan Damjanov, WB Saunders Co., Philadelphia, 2000
Web
Site:
http://health.csusb.edu/dchen
refer to the web site for class materials such as:
lecture notes, study guides, etc.
Prerequisites:
HSCI 120 and
either Bio 223 and 224 or Bio 200, 201 and 202, or consent of the instructor.
Course
Description: Ecological
and medical aspects of human disease and the body’s response to the disease
process and the effects on normal function. 4 units
Course
Objectives:
At the completion of the course, the student should be able to:
1.
list the categories of major diseases and possible causes of these
diseases
2.
understand the diagnostic tests and procedures used by health
practitioners
3.
understand the body’s function and structure in healthy and abnormal
physiological states.
4.
understand the body’s response to the disease processes and their
effects on normal body functions.
5.
write a research paper related to a disease condition of his/her choice.
Grading
System:
A. Points to be obtained:
Term paper (75 pts)
75
Mid
term exams (2 @75)
150
Final
exam
120
Activities
50
Attendance
and class participation
30
Total
425 pts
B.
Letter grades will be assigned according to the following scale:
A
=93-100%
B = 83-86.9%
C = 70-74.9%
D = 55 – 59.9%
A- =
90-92.9%
B- = 80-82.9%
C- = 65-69.9%
D- = 50 – 54.9%
B+
= 87-89.9%
C+ = 75-79.9%
D+ = 60-64.9%
F =
< 49.9%
Last
day to drop class without record:
April 21,
2000, Friday
Final
Exam:
Friday,
June 16, 2000 at 12:00 noon
Note: I am
going to miss several classes this quarter due to out of town meetings.
The classes will be covered by other HSCI faculty; and yes, you will be
responsible for the material covered in my absence.
ASSIGNMENTS
1.
The exams will have multiple-choice, matching, a few true/false types of
questions as well as short answer essay questions.
You will need 2 green Scantron answer sheets for the three exams. Points
(10%) will be deducted for exam taken late without the instructor’s
permission.
Activities
will either be in class or take home assignments to reinforce information
provided for the day. You will need
2 blue books for the activities. There
will be more than 50 points total for the activities and any points over that
will be counted as extra credit points.
2.
Read the
chapters in the textbooks to be covered in the class, this will help to minimize
frantic note taking during class time. Lecture
material will be related to the reading material.
3.
Term Paper - 75 points.
Please refer to the suggested title list and sign up for a topic as soon
as possible.
The
research paper should be between 6 to 10-pages long, double-spaced typed.
Please include a title page with your name only on this title page. Also
turn in a photo-copy of your paper without your name, this copy will be read by
your colleague for additional comments.
In
your paper, you should concentrate on the etiology, pathology, and mechanism of
the disease or condition. Include
at least 5 references in your paper. You
may use web sites in addition to journal or text references, however, please
cite them appropriately. Remember
to turn in a copy of the non-bounded book references used with your paper.
These items will be returned to you with a copy of your paper.
Your
grade will depend on the content, organization, references, editorial comments,
neatness, inclusion of the actual journal articles, and a photocopy of your
paper. Check for correct grammar and editorial content of your
paper, e.g. spelling, punctuations, grammar, etc.
Someone else in the class will read and evaluate your paper anonymously
so please do not include your name anywhere else on your paper.
You
must follow this format for references to get full credit.
Author(s).
title of the article, journal (underline or italic). year, volume:
page numbers.
e.g.
: Smith, J.S., and T.M. Jones,
Diabetes and renal failure. J Am Diet
Assoc. 1997; 90: 12-18.
The references in the body of the paper should have (author, year)
format, not numbering system with footnotes.
Please see me if you have any questions, problems or concerns.
All
written assignments must be typed.
Any assignments submitted that are not typed will have a letter grade
deducted. For example, a paper that
would have been an “A”, if submitted un-typed, will be a “B”.
All
assignments are due by the end of class time on the date it is due unless prior
permission is obtained. Assignments turned in after that time will have a letter
grade deducted for being late, please see me if you have any problems prior
to the due date. For
example, a paper submitted late and un-typed will have 2 letter grades deducted.
Do not hesitate to let me know if you foresee any problems and please do
not hesitate to call me prior to the class meeting time. Don’t forget to include the reference papers used
with the original report. Please submit
a photocopy of your paper/report when you turn it in on the due date.
Thanks....
Date
Topic
Reading Assignment
4/3
Introductions/concepts/cell and body functions
Chapter 1
4/5
Cardiovascular (Dr. Hughes)
Chapter 7
4/7
Cardiovascular (Dr. Hughes)
Chapter 7
4/10
Inflammation,
Chapter 2
4/12
Immune system
Chapter 3
4/14
Immunopathology (cont’d)
Chapter 3
4/17
fluid and hemodynamic disorders
Chapter 6
4/19
Respiratory System
Chapter 8
4/21
Respiratory System cont’d
topic with 3 references due Friday,
4/21
4/24
Midterm 1
Chapters
1, 2, 3, 6, 7, and 8
4/26
Anemias
and hematogpiety system
Chapter 9
4/28
Lymphatic system
cont’d
5/1
GI Disease
Chapter 10
5/3
Vectors and diseases (Dr. Mian)
5/5
Vectors (Dr. Mian)
5/8
GI
disease cont’d
Outline
for the term paper
5/10
Liver and
biliary tract
Chapter 11
5/12
Liver cont’d, pancreas
Chapters 11, 12
5/15
Urinary
Tract
Chapter 13
5/17
midterm 2
Chs
9, 10, 11, 12, 13 & vector
5/19
neoplasm (Dr. Hughes)
Chapter 4
5/22
neoplasm (Dr. Hughes)
5/24
genetic/developmental diseases
(D. Hook)
Chapter 5
5/26
Male Reproductive System
Chapter 14
5/29
Female Reproductive System
Chapter 15
5/31
Endocrine System
Chapter 17
6/2
endocrine system cont’d
Term paper due
6/5
Muscles
Chapter 20
6/7
Nervous system
Chapter 21
6/9
Bones and Joints
Chapter 19
6/16/2000
Friday, 12:00 to 1:50 PM
Final Examination
*
(Subject to change by the instructor, if needed)
Attention:
Please
keep those dates when the assignments are due in mind and please plan ahead. Class participation is encouraged; but if you have
personal discussions, please do so, outside the classroom. It is very distracting to others in the class when you
are talking to each other during the lecture.
Please come to class on time and the first 5 minutes will be devoted to
pop quizzes, or questions and answers that you may have related to the past
lectures or readings.
Health
Science 367
Term Paper Titles
Only
one student may sign up a given topic so please decide on a topic as soon as
possible. Please refer to the tentative schedule for due dates related
to the paper.
1.
Lupus Erythematosus
2.
Drug/alcohol and toxin induced liver diseases
3.
Causes and pathogenesis of infective endocarditis
4.
Pulmonary hypertension
5. Nutrition related anemias
6.
Causes and pathogenesis of Cystic Fibrosis
7.
The nephrotic syndrome
8. Hypertension and minerals
9.
Pathogenesis of Vitamin B6 deficiency
and toxicity
10.
Cushing’s Disease
11.
Muscular dystrophy
12.
Otitis media and breast-fed infants
13. Kaposi’s Sarcoma and relation to cancer
14.
Fibromyalgia/chronic fatigue syndrome
15.
Autoimmune and antinuclear antibodies
16.
Immunologic responses of cell surface receptors
17.
Hodgkin Disease
18.
Lyme Disease
19.
Etiology and pathogenesis of Multiple Sclerosis
20.
Gram negative bacteremia and sepsis syndrome
21.
Chronic Obstructive Pulmonary Disease (COPD)
22.
Pagets disease of the bone
23. Pathogenesis of
osteoporosis
24. Slow virus infections
25.
Calculi (stones) of urinary and biliary systems
26.
Breast cancer or prostate cancer
27.
hypothermia and consequences/treatment
28.
Re-feeding malnourished infants and children
29. Hepatitis
30.
Leukemia
31.
Use of interferon in viral diseases
32.
Herpes
33. Thallasemia
34.
Sickle cell anemia
35. mononucleosis
36.
Growth hormone abnormalities
37.
Functions and mechanism of Cytokines, interleukins, etc.
38.
Diabetes Mellitus, etiology, pathology, etc.
39.
Herbal supplements and immune function - pros and cons
40.
Malaria
41. Parkinson’s Disease
42.
Alzheimer’s Disease
43. Rheumatoid Arthritis
44.
Myasthenia gravis
45. Crohn’s Disease and
ulcerative colitis
46.
Tuberculosis
47.
Gstric/peptic ulcer
48.
decubitis (bed sores)
49. Prader-Willi Syndrome
50.
Syndrome X
51. Autism
52.
Crohn’s disease and ulcerative colitis
53.
Allergy responses
54. Osteoporosis
55.
Others with instructor’s approval: